at night Patients on beta blockers may get relief from their sleep problems with the use of exogenous melatonin.

Geetha .M

» doi: https://jcdponline.org/.2019.v10.i02.pp01-04

Abstract

Beta blockers are known to cause sleep problems. Through the targeted suppression of adrenergic beta1-receptors, beta blockers have been shown to decrease melatonin synthesis. The sleep disorder adverse effects of beta-adrenergic receptor blockers and the danger of reduced melatonin production may be alleviated with the use of exogenous melatonin, which is best taken as a supplement in the evening.