An introduction to lymphatic vessels and their new function in heart disease

Jones , Wang

» doi: https://jcdponline.org/.2019.v10.i02.pp01-10

Abstract

The discovery of markers unique to lymphatic endothelial cells has allowed for the fast acquisition of molecular features of lymphatic vessels (lymphatics) within the last decade. The lymphatic system is an intricate network of vessels that plays a crucial role in normal physiology, apart from the cardiovascular system. In addition to transporting dietary lipids, lymphatic capillaries help with immune surveillance and maintain fluid balance. On the other hand, pathology might be caused by normal lymphatics or worsened by dysfunctional ones. Lymphatic vessels play an important part in both normal bodily functions and disease processes, and this article provides a concise overview of their history of development and progression. Our discussion also includes new evidence linking lymphatic dysfunction to cardiovascular disease.