Impact on plasma natriuretic peptide levels of right ventricular septal pacing compared to apical pacing

Nikoo M. H , Ghaedian M. M

» doi: https://jcdponline.org/.2018.v09.i02.pp01-07

Abstract

This study aims to identify the function of the right ventricle (RV) septal and apical regions by analyzing plasma B-type natriuretic peptide (BNP) levels during pacing in patients with pacemakers. The Methods, Materials, and Results: Research was carried out on seventy-four consecutive patients who fulfilled the requirements for long-term pacing. We split the patients in half according to their pacing mode so that we could do appropriate subgroup analysis. The average age of the 41 patients in one group was 54.1±18.4 years, and they all had dual chamber DDD(R)/ VDD pacemakers. The second group included 33 patients, with an average age of 60.6±18.4 years, who had single chamber VVI pacemakers. A prospective single-blindness based randomization approach was used. At every given point during the implant procedure, a lead was randomly allocated to either the right ventricular septum or the apex of the heart. Compared to the baseline, levels of BNP considerably decreased